Welcome & Registration
08:30–10:30
ISIR council meeting
Location: Building W26, Entrance A, 1st floor, Seminar room 19
08:30–10:00
10:00–10:30 Coffee Break
Session 1: Welcome & Keynote Lectures
10:30–12:00
Chairs: Udo Markert (Germany) & Surendra Sharma (USA)
10:30–10:35
Welcome | Anke Diemert & Sandra M Blois (Germany)10:35–11:10
Maternal tissue immune cells support fetal growth
Francesco Colucci, Medical School Cambridge (UK)11:10–11:45
Transplacental Morse code: Mediators, mechanisms, mice and women
Petra Arck, UKE (Germany)11:45–12:00
Discussion
12:00–13:00 Lunch Break and JRI Board Meeting
room: W26, entrance A, 1st floor, room Kaminzimmer (118)
Session 2: Preeclampsia, cardiovascular Adaptation in pregnancy
13:00–15:00
Chairs: Annetine Staff (Norway) & Tanja Groten (Germany)
13:00–13:25
CD4+ T Cells from Women with Preeclampsia During Pregnancy Contribute to Hypertension, AT1-AA, and Neurovascular Dysfunction in a pregnant rat model of PE.
Babette LaMarca, University of Mississippi (USA)13:25–13:50
Alzheimer’s Disease Etiology in Younger Population: Lessons from Preeclampsia, A Severe Pregnancy Complication
Surendra Sharma, Brown University (USA)13:50–14:15
Molecular subclasses of preeclampsia: potential clinical applications for early detection and personalized prevention
Nandor G. Than, Hungarian Academy of Science (Hungary)14:15–14:25
Plasma level of Placental Protein13 (PP13) in Placental-Derived Extracellular Vesicles (PEV) is elevated in patients with preeclamsia but not in preterm delivery and the impact of corticosteroids.
Marei Sammar, Braude College of Enginering, Biotechnology Engineering (Israel)14:25–14:35
Preeclamptic oocyte donation pregnancies show differences in peripheral T helper 1 and regulatory T cell cytokine profiles compared to uncomplicated oocyte donation pregnancies.
Kim van Bentem, Leiden University Medical Center (Netherlands)14:35–14:45
Regulatory functions of placental galectins at the maternal-fetal interface and their impairment in pregnancy complications associated with inflammation.
Andrea Balogh, Eötvös Loránd Research Network (Hungary)14:45–14:55
Preeclampsia-associated vascular aging (PAVA) – senescence induction in endothelial cells in the context of preeclampsia pathophysiology.
Lena Lode, Jena University Hospital (Germany)
15:00–15:30 Coffee Break
Session 3: Preventive medicine approaches
15:30–16:40
Chair: Natalie Ledee (France) & Gabriela Dveksler (USA)
15:30–16:00
Multiomic Modeling and Data-Driven Selection of Reliable Biomarkers for Predicting Pregnancy Complications
Brice Gaudilliere, Stanford University (USA)16:00–16:10
Elevated endometrial T-bet/GATA3 ratio predicts reproductive failure in infertile patients during the peri-implantation period.
Yuye Li, Shenzhen Zhongshan Urology Hospital (China)16:10–16:20
The composition of the endometrial microbiota alters the endometrial immune environment and significantly impacts clinical outcomes of assisted reproduction treatments.
L. Medina-Ruiz, IGLS (Spain)16:20–16:30
The investigation of endometrial microbiota and its possible role in IVF success.
Eva Miko, University of Pécs (Hungary)16:30–16:40
Evaluation of the proangiogenic role of the complement component C1q in endometriosis
Chiara Agostinis, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste (Italy)
Express Presentation Session
16:40–19:30
Chairs: Kristin Thiele (Germany), Joanne Kwak Kim (USA), Brice Gaudilliere (USA)